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Nizoral has been shown to cause serious and sometimes fatal liver problems. Contact your doctor immediately if you experience symptoms of liver toxicity such as unusual fatigue, yellowing of the eyes or skin, dark urine, pale stools, loss of appetite, abdominal pain, vomiting, or severe or persistent nausea. Your doctor will perform liver function tests before you begin taking Nizoral and periodically during treatment. Use of Nizoral along with certain other medicines may increase your risk of serious and sometimes fatal heart problems, including irregular heartbeat. Do not take Nizoral if you are also taking astemizole, cisapride, or terfenadine.

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